Welcome to the REFRESH Bioinformatics Group

We are a group of researchers developing various tools for bioinformatics data analysis and processing. Our aim is to tackle complex bioinformatics problems that require a lot of resources (time, memory) and design algorithms (as well as implement them) as efficent as possible (in terms of results quality, time, and memory requirements). Our most popular tools are: KMC (k-mer counter), FAMSA (multiple sequence alignment of proteins for huge datasets), CoLoRd (cutting-edge compressor for 3rd generation sequencing data), Kmer-db (k-mer-based tools for large-scale analyses of nucleotide datasets), AGC (compressor of collections of assembled genomes).

We are a part of the Department of Algorithms and Software of Silesian University of Technology, Gliwice, Poland. Nevertheless, some of our tools were prepared in close collaboration with researchers from various universities.

News

24 Dec 2024

Paper describing sc-SPLASH, SPLASH2 extension for single-cell data is deposited in bioRxiv.org.

23 Oct 2024

Paper about painting genomes using a colored de Bruijn graph is now at NAR GAB.

23 Sep 2024

Paper introducing SPLASH2 for unsupervised discovery from raw sequencing reads is published in Nature Biotechnology.

10 Jul 2024

Paper describing ProteStAr, our CIF/PDF file compressor is published in Bioinformatics.

2 Jul 2024

Preprint describing Vclust, ultrafast and accurate sequence alignment and clustering of viral genomes is deposited in bioRxiv.org.

25 May 2024

Preprint describing application of SPLASH2 for reference-free discoveries in plants is deposited in bioRxiv.org.

18 Mar 2024

AGC 3.1 (assembled genome compressor) is published.

26 Jan 2024

Paper describing new version of RECKONER, our read corrector is published in Scientific Reports.

22 Jan 2024

Paper describing discoveries made by SPLASH in microbial data is deposited in bioRxiv.

... see all News